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>> Home >> 5-HTP 100 mg

5-HTP 100 mg

30 capsules
by Karuna

Categories: Amino Acids, Nucleic Acids, and Peptides, Brain/Nerves
Retail Price: $23.70, Your Price: $20.95 (You save 12%!)
Buy 6-11 of this item, and your price becomes $19.90 each! (You save 16%!)
Buy 12 or more, and your price becomes $18.86 each! (You save 20%!)


What is it?

5-HTP is 5-hydroxytryptophan, the amino acid from which the body makes serotonin. It is a metabolite of L-Tryptophan. Each capsule contains 100 mg of 5-HTP (Griffonia simplicifolia).

According to the manufacturer:

"5-Hydroxytryptophan is the direct precursor to serotonin, an important neurotransmitter that participates in the regulation of emotional mood, sleep/wake cycles, pain thresholds, and appetite."


One review of 17 studies of 5-HTP concluded that it was relatively free of side effects. Large doses of over 200 mg sometimes caused mild nausea but not enough to stop taking it. However, there are precautions!
5-HTP should not be taken with other antidepressants, MAO inhibitors, weight loss products, St.John's wort*, or by pregnant women, unless recommended by a health practitioner. Vitamin B6 should not be taken at the same time, although it is helpful if taken about 6 hours earlier than the 5-HTP.
If you have any of these diseases or conditions see your doctor before taking 5-HTP.
Cardiovascular Diseases (high blood pressure, post-stroke, post-heart attack); Extremely Elderly Persons; those with Parkinson's Disease, Cancer or Autoimmune Diseases (Scleroderma, Rheumatoid Arthritis, Multiple Sclerosis, Lupus); Lung Diseases; Chronic Alcoholism; Liver diseases (hepatitis or cirrhosis); parasitic infection; AIDS; Anorexia Nervosa; Low protein Diets; Allergies (severe); Myalgia (persistent pain and weakness of the muscles); Peripheral Neuropathy (pain weakness of the muscles); Rash or Flushing; Edema; Nausea; Diarrhea; Sickle cell anemia; hemophilia; Pregnancy.
Those with AIDS, cancer, autoimmune diseases and the very elderly have an increased risk of fibrosis because of an enzyme that is frequently elevated in these conditions. Fibrosis is the deposition of connective tissue in internal organs.
5-HTP along with chronic alcoholism and liver disease caused heart fibrosis in animals. Alcohol inhibits the metabolism of 5-HTP.
Concurrent drug use: 5-HTP should not be used if taking: Anti-depressant drugs; Monoamine oxidase inhibitors; Selective Serotonin Reuptake Inhibitors (SSRI's e.g., Prozac); Tricyclic medications; Weight Loss medications (i.e., dexfenfluramine); Anti-parkinson medications (e.g., L-dopa); Barbiturates and other tranquilizing drugs; Antihistamines and cold medications; Alcoholic beverages; Intravenous (illegal I.V.) drugs; Cancer chemotherapy or antibiotic medications.
Warning: Dosages of 5-hydroxy L-tryptophan (5-HTP) greater than 100 milligrams per day should be taken only under the guidance of a physician. 5-HTP can increase the effect of tranquilizing drugs and can impair the ability to drive an automobile.

See Disclaimer.

Suggested Use

Start with one capsule daily before meals or at bedtime, or as directed. Then after two weeks move to one capsule twice daily. If this is inadequate then one capsule 3 times daily may be tried. It should be taken 20 minutes before meals or with a carbohydrate source such as fruit or fruit juice. It should also be taken with its co-factors such as niacin, magnesium and Vitamin B6 (not at the same time.)

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